Tetracycline

Tetracycline
	[[File:\|250px]]; Chemical structure of tetracycline
Formula	C22H24N2O8
Administration	Oral (capsules, tablets), intravenous, intramuscular, topical
Solubility	Very slightly soluble in water; freely soluble in dilute acids and alkali hydroxide solutions
Legal status	Prescription only
Brand names	Sumycin, Achromycin V, Tetracyn, Panmycin
Bioavailability	60–80% (oral, fasting)
Recommended dose	250–500 mg orally every 6 hours (mild to moderate infections); up to 500 mg every 6 hours (severe infections)
Upper limit	2 g/day (maximum recommended; reduce in renal impairment)
LD50	>5000 mg/kg (rat, oral)

Introduction

Tetracycline
[[File:\|250px]] Chemical structure of tetracycline
Formula	C₂₂H₂₄N₂O₈
Administration	Oral (capsules, tablets), intravenous, intramuscular, topical
Solubility	Very slightly soluble in water; freely soluble in dilute acids and alkali hydroxide solutions
Legal status	Prescription only
Brand names	Sumycin, Achromycin V, Tetracyn, Panmycin
Bioavailability	60–80% (oral, fasting)
Recommended dose	250–500 mg orally every 6 hours (mild to moderate infections); up to 500 mg every 6 hours (severe infections)
Upper limit	2 g/day (maximum recommended; reduce in renal impairment)
LD50	>5000 mg/kg (rat, oral)