Doxycycline
From WikiPeatia
| Doxycycline | |
|---|---|
| [[File:|250px]] Chemical structure of doxycycline | |
| Formula | C22H24N2O8 |
| Administration | Oral (tablets, capsules, suspension), intravenous |
| Solubility | Very slightly soluble in water; soluble in methanol, ethanol |
| Legal status | Prescription only |
| Brand names | Vibramycin, Oracea, Doryx, Monodox, Periostat |
| Bioavailability | 73–95% (oral) |
| Recommended dose | 200 mg on day 1 (100 mg every 12 hours), then 100 mg once daily (up to 200 mg/day for severe infections) |
| Upper limit | 300 mg/day (general; up to 600 mg/day for gonorrhea under supervision) |
| LD50 | >2000 mg/kg (rat, oral) |
