Roadmap/03 - Self diagnosis & markers

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Diagnosing symptoms

Thyroid - Temperature and heart rate

“Oral or armpit temperature in the morning, before getting out of bed, should be around 98° F [36.6º C], and it should rise to 98.6° F [37.1º C] by mid-morning. […] Healthy populations have an average resting pulse rate of about 85 per minute.” - Ray Peat

Markers of health Ideal Before After breakfast
Temperature 98.6 - 99F 37.0° - 37.2°C
Heart rate 85 - 90 BPM
  • Unnderarm/oral temperature and pulse upon waking and midday.
  • Track daily averages
    • aim for steady rises with changes.
  • Post-meal temperature
    • should rise if metabolism is healthy (fuel burning); if it drops, stress hormones may dominate.

List of blood tests

Marek online blood test

Idealabs steroid analysis

Marker Male Female
Prolactin in men 4-7 ng/ml (85–150 mU/L) female 1-12 ng/ml
Total Cholesterol 160 - 200 mg/dl
RT3 Standard
CRP Standard
TSH Below 1, as close to 0 as possible
PTH 15 pg/ml
CO2 30 mmol/l
Serum calcium 9 mg/dl
Serum phosphate 3 mg/dl

Self Tracking

Extended self tracking table

Link to tracking

Body markers

If your hands are warm and you feel kind and energetic, you’re doing it right. If you’re cold and cranky, something is wrong

Tongue

Ideal

  • Should be pink, smooth

Symptoms

  • White = SIBO or candida
  • Cracks = you're screwed, maybe some defficiency

Nails & Fingers

Ideal

  • Fast-growing
  • Nailbeds should be pink
    • means tissue is retaining CO2

Symptoms

  • White horizontal lines = zinc defiiciency
  • Clubbed fingers = heart disease
  • Brittle nails = lack of gelatin, vitamin D and calcium in the diet
  • White moons at the bottom?

Eyebrows

Ideal

  • Full

Symptoms

  • Queen Anne's sign = Thinning or loss of the outer third of the eyebrows is one of the physical manifestations of hypothyroidism[1]
  • Eye

Ideal

  • Focused, calm and alert

Symptoms

  • Eye bags = Low thyroid, gut irritation, tired
  • Bulging = Grave's disease, (easily misdiagnosed as hyperthyroidism)
  • Dark circles under the eyes = vitamin C status + impaired collagen production, oxidative stress

Hair

Ideal

  • Full head of hair

Symptoms

  • Thinning/norwood = high prolactin and everything

Earlobe

Ideal

  • Smooth

Symptoms

  • Crease = heart disease or circulatory disorder

Face skin

Ideal

  • Baby

Symptoms

  • General puffiness around the face (edema) = high estrogen
  • Crow's feet = impaired collagen / elastin production of the skin
    • Oxidative stress
    • Low vitamin C status
    • Poor collagen intake
    • Low glycine intake

Lips

Ideal

  • Kissable

Symptoms

  • Chapped lips = dehydration caused by lack of sealing
    • Chronic inflammation, especially from the gut
    • Hypothyroidism
    • Poor saliva production (low cholinergic / parasympathetic tone)
    • Defficiencies[2]

Body skin

Ideal

  • Smooth, elastic, without spots

Symptoms

  • Cellulite = high estrogen, high PUFA
  • Thinning skin (ungrabable) = low thyroid
  • Lipufuscin spots (liver spots) = high PUFA, high iron
  • Yellow skin = liver problems, high keratine,
  • Cracks, ashy knees & elbows = low vitamin A
  • Hives, itchiness = high histamine
  • Melasma = excess estrogen upregulating melanin

Veins

Ideal

  • Smooth, elastic, without spots

Symptoms

  • Bulging veins = high estrogen, especially on the back of the hand

Women's breasts

Ideal

  • Firm, perky

Symptoms

  • Tender = high estrogen
  • Sagging

Men's chest

Ideal

  • Developped like a man's

Symptoms

  • Gynecomastia = high estrogen and prolactin

Extremities

Ideal

  • Warm, circulated

Symptoms

  • Cold feet, hair, nose = high adrenaline
  • If it takes long to pink after a squeze

Sweat glands

Ideal

  • Moderate amount, non-stinky

Symptoms

  • Inability to sweat = low thyroid

Nose

Ideal

  • Reasonably dry

Symptoms

  • Runny = high histamine

Posture

Ideal

  • Straight, non tense

Symptoms

  • Postural issues = Low androgen (DHT)

Tummy

Ideal

  • Flat(ish)

Symptoms

  • Bulging gut = high HGH, general SIBO
    • Could also be visceral fat accumulation or weak abdomenal muscles/PSOAs

Movement

Ideal

  • Normal, balanced, free-flowing

Symptoms

  • Movement disorders, twitches = high serotonin

Energy levels

Ideal

  • Warm, calm, sociable, libido, good sleep, no brain fog

Symptoms

  • Fatigue = low T3

Apetite

Ideal

  • Healthy

Symptoms

  • Low apetite
  • Overeating/stress eating

Achilles reflex speed

Ideal

  • Fast relaxation phase (film yourself dropping foot)

Symptoms

  • Slow/hanging reflex

Bronda Barnes chart of common hypothyroidism symptoms[3]

Symptom % prevalence in hypothyroidism
Weakness 98.5
Sensation of cold 92
Dry skin 88
Lethargy 88
Edema of eyelids 88
Edema of face 87
Coarse skin 83.5
Cold skin 81.5
Decreased sweating 78.5
Coarseness of hair 75.5
Slow speech 73.5
Slow movements 73
Thick tongue 71
Heart enlargement 68
Gain in weight 67.5
Impaired memory 65.5
Labored or difficult breathing 63.5
Hoarseness 63
Muscle weakness 61
Depression 60
Pallor of skin 58.5
Constipation 57.5
Swelling of feet 56
Burning or tingling sensations 56
Pallor of lips 53.5
Loss of hair 49
Slowing of mental activity 49
Nervousness 43
Loss of appetite 42.5
Brittle nails 41
Muscle pain 36
Deafness 35
Excessive menstruation 32.5
Poor heart sounds 30
Joint pain 29
Palpitations 27
Poor vision 24
Pain over the heart 20.5
Changes in back of eye 20
Painful menstruation 18
Loss of weight 11
Emotional instability 11
Choking sensation 9
Fineness of hair 9
Cyanosis (bluish skin) 9
Difficulty in swallowing 3
Heat intolerance 2

Iodine defficiency

"The skin test of iodine deficiency is completely unscientific. Iodine is converted to colorless iodide by reductants, including vitamin C, glutathione, and thiosulphate... The test is completely irrational. It implies that the body should be saturated with iodine.” - Ray Peat

Excessive amounts of iodide have been linked to the development of autoimmune thyroiditis in humans and animals[4]

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References